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In collaboration with Prof. Yves Dory,
we investigate the self-assembled nanotubes and their organization of cyclic
peptides in liquid crystals and polymers. This project aims at revealing the
effects of liquid crystal and polymer mediums on the self-assembled structures
of cyclic peptides and developing new strategies to manipulate peptide
nanotubes.
Representative publication:
“Micrometer-Sized Hexagonal Tubes Self-Assembled by a Cyclic Peptide in
a Liquid Crystal” Angew. Chem. Int. Ed., 2004, 43,
349-353.
Scanning electron microscope image of a large
hexagonal hollow tube formed by a cyclic peptide in a nematic
liquid crystal. The computer modeling illustrates the proposed
hierarchical and self-similar process of self-assembly.
